Serotonin
- ist ein Neurotransmitter, der viele verschiedene Informationen übergibt.
- wird vom Enzym tryptophan hydroxylase produziert
- ein niedriges Level von Serotonin im Körper wird mit einer höheren Aggressionsbereitschaft verbunden
- es fördert behavioral und cognitive antisocial impulsivity in Lebewesen, die ohnehin schon anfällig für impulsivity waren
- fast alles serotonin wird im raphe nucleus hergestellt
- most receptors are metabotropic
- 5-HT (5-Hydroxytryptamine): Chemical name for serotonin.
- Function: Acts as a Neurotransmitter, transmitting signals in the nervous system.
- Roles:
- Mood regulation: Key in maintaining mood balance; implicated in depression and anxiety.
- Digestion: Influences gut motility and secretion.
- Sleep: Regulates sleep cycles and wakefulness.
- Appetite: Affects eating behavior and satiety.
- Pain Perception: Modulates pain pathways and can affect how pain is perceived.
- Synthesis: Produced from the amino acid tryptophan through a biochemical conversion process.
- Pathways: Operates across various brain regions, including the Central Nervous System (CNS) and enteric nervous system in the gut.
- Receptors: Binds to multiple Serotonin (5-HT) receptors (5-HT receptors), each mediating different physiological responses.
- Clinical significance: Target for many psychiatric medications, including SSRIs (Selective Serotonin Reuptake Inhibitors) which increase serotonin levels in the brain to treat depression and anxiety disorders.
Funktionen:
- mood
- memory processing
- Sleep, Schlaf
- Cognition
- und andere physiologische Prozesse wie z.B. Übergeben und Gefäßverengung
aus Behave
low levels of serotonin in the brain were shown to be associated with elevated levels of human Aggression
(p.75)
So a decrease in serotonin levels increases impulsivity.
⇒ [[Behave#Chapter 2 One Second Before#The mesolimbic mesocortical Dopamine System]]
See also
Superlink:
tags: HormoneNeurotransmitter science
L-Tryptophan
tryptophan hydroxylase
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Erstellt: 26-07-21 20:42
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